If people stop medication, many are likely to need ongoing nutritional and behavioural support, and health services should anticipate that cardiometabolic benefits may lessen as weight is regained, Spreckley said, adding that this highlights the need for further research into effective, scalable strategies for long-term weight maintenance alongside pharmacotherapy. GLP-1 medications have become widely used in recent years, and more than 15 million Americans are now losing weight with the drugs
Patients who are sensitive to stimulants may also benefit from topiramate, as it does not increase heart rate or blood pressure
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Source: Endocrine Society, ENDO 2026 Annual Meeting press release, June 13, 2026.
The study kicked off after multiple people at Mass Eye and Ear realized a trend with three patients in their practice getting a vision loss diagnosis from NAION in just one week, all taking semaglutide